diff --git a/.flake8 b/.flake8
new file mode 100644
index 00000000..d4dd51ed
--- /dev/null
+++ b/.flake8
@@ -0,0 +1,12 @@
+[flake8]
+max_line_length = 120
+ignore =
+    # allow empty line at end of file
+    W391,
+    # break before binary operator - allow either style
+    W503,
+    # break after binary operator - allow either style
+    W504,
+exclude =
+  .git,
+  venv
diff --git a/.github/workflows/coverage.yml b/.github/workflows/coverage.yml
index b2d1b91c..52e0dec2 100644
--- a/.github/workflows/coverage.yml
+++ b/.github/workflows/coverage.yml
@@ -24,7 +24,7 @@ jobs:
         python -m pytest --cov --cov-config=.coveragerc
 
     - name: Submit report to codecov
-      uses: codecov/codecov-action@v5
+      uses: codecov/codecov-action@v7
       with:
         token: ${{ secrets.CODECOV_TOKEN }}
       if: success()
diff --git a/.github/workflows/style.yml b/.github/workflows/style.yml
index ebc24701..4977a6c3 100644
--- a/.github/workflows/style.yml
+++ b/.github/workflows/style.yml
@@ -25,5 +25,5 @@ jobs:
 
     - name: Check imports are ordered correctly
       run: |
-        python -m isort --verbose --check-only --diff cellmlmanip tests setup.py
+        python -m isort --verbose --check-only --diff cellmlmanip tests
 
diff --git a/pyproject.toml b/pyproject.toml
index 7b959378..7dc687b6 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -1,3 +1,70 @@
 [build-system]
 requires = ["setuptools>=64", "wheel"]
 build-backend = "setuptools.build_meta"
+
+[project]
+name = "cellmlmanip"
+description = "CellML loading and model equation manipulation"
+readme = "README.md"
+requires-python = ">=3.10"
+authors = [
+    {name = "Asif U Tamuri"},
+    {name = "Sarah M Keating"},
+    {name = "Maurice Hendrix"},
+    {name = "Michael Clerx"},
+    {name = "Jonathan Cooper", email = "j.p.cooper@ucl.ac.uk"},
+]
+classifiers = [
+    "Programming Language :: Python :: 3",
+    "Programming Language :: Python :: 3.10",
+    "Programming Language :: Python :: 3.11",
+    "Programming Language :: Python :: 3.12",
+    "Programming Language :: Python :: 3.13",
+    "Programming Language :: Python :: 3.14",
+    "License :: OSI Approved :: BSD License",
+    "Operating System :: OS Independent",
+]
+dependencies = [
+    "lxml>=4.7",
+    "networkx>=2.1",
+    "Pint>=0.24, <0.26",
+    "rdflib>=4",
+    "sympy>=1.4, <1.13",
+]
+dynamic = ["version"]
+
+[project.optional-dependencies]
+docs = [
+    "sphinx>=2.0",
+]
+test = [
+    "flake8",
+    "isort",
+    "pytest>=6.0",
+    "pytest-cov",
+]
+
+[project.urls]
+Homepage = "https://github.com/ModellingWebLab/cellmlmanip"
+
+[tool.setuptools]
+include-package-data = true
+
+[tool.setuptools.dynamic]
+version = {file = "cellmlmanip/version.txt"}
+
+[tool.setuptools.packages.find]
+exclude = ["tests*", "docs*"]
+
+[tool.isort]
+line_length = 120
+multi_line_output = 3
+# ^ Vertical Hanging Indent
+force_grid_wrap = 4
+# ^ Don't allow more than 3 imports on a single line
+lines_after_imports = 2
+order_by_type = true
+include_trailing_comma = true
+force_single_line = false
+default_section = "THIRDPARTY"
+known_first_party = ["cellmlmanip"]
diff --git a/setup.cfg b/setup.cfg
deleted file mode 100644
index bd511cfd..00000000
--- a/setup.cfg
+++ /dev/null
@@ -1,27 +0,0 @@
-[flake8]
-max_line_length = 120
-ignore =
-    # allow empty line at end of file
-    W391,
-    # break before binary operator - allow either style
-    W503,
-    # break after binary operator - allow either style
-    W504,
-exclude =
-  .git,
-  venv
-
-[isort]
-line_length = 120
-multi_line_output = 3
-# ^ Vertical Hanging Indent
-force_grid_wrap = 4
-# ^ Don't allow more than 3 imports on a single line
-lines_after_imports = 2
-order_by_type = True
-include_trailing_comma = True
-force_single_line = False
-
-default_section = THIRDPARTY
-known_first_party = cellmlmanip
-skip =
diff --git a/setup.py b/setup.py
deleted file mode 100644
index b97b0c91..00000000
--- a/setup.py
+++ /dev/null
@@ -1,55 +0,0 @@
-import os
-
-from setuptools import find_packages, setup
-
-
-# Load README
-with open('README.md') as f:
-    readme = f.read()
-
-# Load version number
-with open(os.path.join('cellmlmanip', 'version.txt'), 'r') as f:
-    version = f.read()
-
-setup(
-    name='cellmlmanip',
-    version=version,
-    description='CellML loading and model equation manipulation',
-    long_description=readme,
-    long_description_content_type='text/markdown',
-    author='Asif U Tamuri, Sarah M Keating, Maurice Hendrix, Michael Clerx, Jonathan Cooper',
-    author_email='j.p.cooper@ucl.ac.uk',
-    url='https://github.com/ModellingWebLab/cellmlmanip',
-    classifiers=[
-        'Programming Language :: Python :: 3',
-        'Programming Language :: Python :: 3.10',
-        'Programming Language :: Python :: 3.11',
-        'Programming Language :: Python :: 3.12',
-        'Programming Language :: Python :: 3.13',
-        'Programming Language :: Python :: 3.14',
-        'License :: OSI Approved :: BSD License',
-        'Operating System :: OS Independent',
-    ],
-
-    packages=find_packages(exclude=('tests', 'docs')),
-    include_package_data=True,
-    python_requires='>=3.10',
-    install_requires=[
-        'lxml>=4.7',
-        'networkx>=2.1',
-        'Pint>=0.24, <0.26',
-        'rdflib>=4',
-        'sympy>=1.4, <1.13',
-    ],
-    extras_require={
-        'docs': [
-            'sphinx>=2.0',
-        ],
-        'test': [
-            'flake8',
-            'isort',
-            'pytest>=6.0',
-            'pytest-cov',
-        ],
-    },
-)