RocaSec: A standalone GUI-based package for robust co-evolutionary analysis of proteins
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Updated
Dec 18, 2019
RocaSec: A standalone GUI-based package for robust co-evolutionary analysis of proteins
A GLUE project for Hepatitis C virus (HCV)
Provider-side oncology prior-authorization copilot · 7-agent LangGraph DAG · AWS Bedrock + Claude Sonnet 4.6 · CMS-0057-F native
HCV drug resistance extension based on collaboration with PHE.
This project is for hepatitis class prediction based on the constituting blood features.
HCV is categories in many Genotypes as differentiating with a sequence alignment of nucleotide (genetic Material (ssRNA(+)) of HCV with host ribosome endoplasmic reticulum of hepatocyte cells. The dataset presents HCV Sub-Genotypes 1a, 1b, 1c, 2a, 2b, 2c, 3a, 3b, 4a, 5a, 6a, 6b, 6g
Model of hepatitis C transmission in Norway used in Whittaker, Midtbø and Kløvstad (https://doi.org/10.1093/infdis/jiae147, 2024)
The CDAF-Relink Data Dictionary is a REDCap based repository for managing relinkage to care for HCV- and HBV-infected individuals.
A multi-omic bioinformatics pipeline interrogating viral translational hijacking in HCV-infected hepatoma cells. By integrating Ribosome Profiling and RNA-seq, it quantifies translational efficiency, maps ribosomal pause sites, and correlates translational stalling with RNA thermodynamic stability.
Extension to HCV-GLUE - contains all published HCV data from NCBI, plus analysis logic for HCV genomes.
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